Function and Biology

CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY WITH A BOUND IMIDO DIPHOSPHATE

EC 2.7.13.3: Histidine kinase

Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Systematic name:
ATP:protein-L-histidine N-phosphotransferase
Alternative Name(s):
  • EnvZ
  • HK1
  • HP165
  • Histidine protein kinase
  • Protein histidine kinase
  • Protein kinase
  • Protein kinase (histidine)
  • Sln1p

Sequence families

Pfam Protein families (Pfam)
PF09078
Domain description: CheY binding
Occurring in:
  1. Chemotaxis protein CheA
The deposited structure of PDB entry 1ffw contains 2 copies of Pfam domain PF09078 (CheY binding) in Chemotaxis protein CheA. Showing 1 copy in chain B.

PF00072
Domain description: Response regulator receiver domain
Occurring in:
  1. Chemotaxis protein CheY
The deposited structure of PDB entry 1ffw contains 2 copies of Pfam domain PF00072 (Response regulator receiver domain) in Chemotaxis protein CheY. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001789
Domain description: Signal transduction response regulator, receiver domain
Occurring in:
  1. Chemotaxis protein CheY
IPR035891
Domain description: CheY-binding domain of CheA
Occurring in:
  1. Chemotaxis protein CheA
IPR015162
Domain description: CheY binding
Occurring in:
  1. Chemotaxis protein CheA
IPR011006
Domain description: CheY-like superfamily
Occurring in:
  1. Chemotaxis protein CheY

Structure domains

CATH CATH domains
3.30.70.400
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: CheY-binding domain of CheA
Occurring in:
  1. Chemotaxis protein CheA
The deposited structure of PDB entry 1ffw contains 2 copies of CATH domain 3.30.70.400 (Alpha-Beta Plaits) in Chemotaxis protein CheA. Showing 1 copy in chain B.
3.40.50.2300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Chemotaxis protein CheY
The deposited structure of PDB entry 1ffw contains 2 copies of CATH domain 3.40.50.2300 (Rossmann fold) in Chemotaxis protein CheY. Showing 1 copy in chain A.
SCOP SCOP annotations
55053
Class: Alpha and beta proteins (a+b)
Fold: Ferredoxin-like
Superfamily: CheY-binding domain of CheA
Occurring in:
  1. Chemotaxis protein CheA
The deposited structure of PDB entry 1ffw contains 2 copies of SCOP domain 55053 (CheY-binding domain of CheA) in Chemotaxis protein CheA. Showing 1 copy in chain B.
52173
Class: Alpha and beta proteins (a/b)
Fold: Flavodoxin-like
Superfamily: CheY-like
Occurring in:
  1. Chemotaxis protein CheY
The deposited structure of PDB entry 1ffw contains 2 copies of SCOP domain 52173 (CheY-related) in Chemotaxis protein CheY. Showing 1 copy in chain A.