1fd4

X-ray diffraction
1.7Å resolution

HUMAN BETA-DEFENSIN 2

Released:

Function and Biology Details

Biochemical function:
Cellular component:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-defensin 4A Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 41 amino acids
Theoretical weight: 4.34 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O15263 (Residues: 24-64; Coverage: 100%)
Gene names: DEFB102, DEFB2, DEFB4, DEFB4A, DEFB4B
Sequence domains: Beta defensin
Structure domains: Antimicrobial Peptide, Beta-defensin 2; Chain A

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P21
Unit cell:
a: 54.525Å b: 79.95Å c: 74.271Å
α: 90° β: 105.3° γ: 90°
R-values:
R R work R free
0.188 0.188 0.264
Expression system: Not provided