› 1f8x

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE

Released:
DOI: 10.2210/pdb1f8x/pdb
PDB entry 1f8x coloured by chain, front view.
PDB entry 1f8x coloured by chain, side view.
PDB entry 1f8x coloured by chain, top view.
Source organism: Lactobacillus leichmannii
Primary publication:
Crystal structures of nucleoside 2-deoxyribosyltransferase in native and ligand-bound forms reveal architecture of the active site.
Armstrong SR, Cook WJ, Short SA, Ealick SE
Structure 4 97-107 (1996)
PMID: 8805514

Function and Biology Details

Reaction catalysed: 
2-deoxy-D-ribosyl-base(1) + base(2) = 2-deoxy-D-ribosyl-base(2) + base(1)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside deoxyribosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 157 amino acids
Theoretical weight: 18.1 KDa
Source organism: Lactobacillus leichmannii
UniProt:
  • Canonical: Q9R5V5 (Residues: 1-157; Coverage: 100%)
Gene name: ntd
Sequence domains: Nucleoside 2-deoxyribosyltransferase
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: I213
Unit cell:
a: 151Å b: 151Å c: 151Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.166 0.24

Quick links

Citations

3 review citations

Nucleotide metabolism and its control in lactic acid bacteria.
Kilstrup et al. (2005)
2 more

3 mentions without citation

Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Sikowitz et al. (2013)
2 more