› › Structure analysis

2.6 A CRYSTAL STRUCTURE OF A NUCLEOSOME CORE PARTICLE CONTAINING THE VARIANT HISTONE H2A.Z

X-ray diffraction
2.6Å resolution
PDB entry 1f66 coloured by chain, front view.
PDB entry 1f66 coloured by chain, side view.
PDB entry 1f66 coloured by chain, top view.
Source organisms:
Assembly composition:
hetero decamer (preferred)
Entry contents: 4 distinct polypeptide molecules
1 distinct DNA molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Nucleosome, Histone and DNA
hide full assembly name
Multimeric state: hetero decamer
Accessible surface area: 74433.89 Å2
Buried surface area: 57812.17 Å2
Dissociation area: 3,964.59 Å2
Dissociation energy (ΔGdiss): 64.75 kcal/mol
Dissociation entropy (TΔSdiss): 13.12 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-113792

Macromolecules

Histone H3.2
Chains: A, E
Length: 136 amino acids
Theoretical weight: 15.51 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: P84233 (Residues: 1-136; Coverage: 100%)
Pfam: Core histone H2A/H2B/H3/H4
InterPro:
CATH: Histone, subunit A
SCOP: Nucleosome core histones
Histone H3.2 in PDB entry 1f66, assembly 1, front view.
Histone H3.2 in PDB entry 1f66, assembly 1, side view.
Histone H3.2 in PDB entry 1f66, assembly 1, top view.
Molecule details ›

Search similar proteins

Histone H4
Chains: B, F
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P62806 (Residues: 1-103; Coverage: 100%)
Gene names: H4-12, H4-53, H4c1, H4c11, H4c12, H4c14, H4c16, H4c2, H4c3, H4c4, H4c6, H4c8, H4c9, H4f16, Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4, Hist2h4a, Hist4h4
Pfam: Centromere kinetochore component CENP-T histone fold
InterPro:
CATH: Histone, subunit A
SCOP: Nucleosome core histones
Histone H4 in PDB entry 1f66, assembly 1, front view.
Histone H4 in PDB entry 1f66, assembly 1, side view.
Histone H4 in PDB entry 1f66, assembly 1, top view.
Molecule details ›

Search similar proteins

Histone H2A.Z
Chains: C, G
Length: 128 amino acids
Theoretical weight: 13.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0C0S5 (Residues: 1-128; Coverage: 100%)
Gene names: H2AFZ, H2AZ, H2AZ1
Pfam:
InterPro:
CATH: Histone, subunit A
SCOP: Nucleosome core histones
Histone H2A.Z in PDB entry 1f66, assembly 1, front view.
Histone H2A.Z in PDB entry 1f66, assembly 1, side view.
Histone H2A.Z in PDB entry 1f66, assembly 1, top view.
Molecule details ›

Search similar proteins

Histone H2B 1.1
Chains: D, H
Length: 126 amino acids
Theoretical weight: 13.98 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: P02281 (Residues: 1-126; Coverage: 100%)
Pfam: Core histone H2A/H2B/H3/H4
InterPro:
CATH: Histone, subunit A
SCOP: Nucleosome core histones
Histone H2B 1.1 in PDB entry 1f66, assembly 1, front view.
Histone H2B 1.1 in PDB entry 1f66, assembly 1, side view.
Histone H2B 1.1 in PDB entry 1f66, assembly 1, top view.
Molecule details ›

Search similar proteins

DNA chains I, J
Name: PALINDROMIC 146 BASE PAIR DNA FRAGMENT
Representative chains: I, J
Length: 146 nucleotides
Theoretical weight: 45.05 KDa
PALINDROMIC 146 BASE PAIR DNA FRAGMENT in PDB entry 1f66, assembly 1, front view.
PALINDROMIC 146 BASE PAIR DNA FRAGMENT in PDB entry 1f66, assembly 1, side view.
PALINDROMIC 146 BASE PAIR DNA FRAGMENT in PDB entry 1f66, assembly 1, top view.
Molecule details ›

Search similar DNA

Quick links