PDBe 1esr

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF HUMAN MONOCYTE CHEMOTACTIC PROTEIN-2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 8 Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80075 (Residues: 24-99; Coverage: 100%)
Gene names: CCL8, MCP2, SCYA10, SCYA8
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P6122
Unit cell:
a: 61.012Å b: 61.012Å c: 114.926Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.232 0.32
Expression system: Escherichia coli