Function and Biology

CRYSTAL STRUCTURE OF ACID PHOSPHATASE FROM ESCHERICHIA BLATTAE COMPLEXED WITH THE TRANSITION STATE ANALOG MOLYBDATE

Source organism: Shimwellia blattae
Biochemical function: acid phosphatase activity
Biological process: not assigned
Cellular component: outer membrane-bounded periplasmic space

EC 3.1.3.2: Acid phosphatase

Reaction catalysed:
A phosphate monoester + H(2)O = an alcohol + phosphate
Systematic name:
Phosphate-monoester phosphohydrolase (acid optimum)
Alternative Name(s):
  • Acid monophosphatase
  • Acid nucleoside diphosphate phosphatase
  • Acid phosphohydrolase
  • Acid phosphomonoester hydrolase
  • Acid phosphomonoesterase
  • Glycerophosphatase
  • Orthophosphoric-monoester phosphohydrolase (acid optimum)
  • Phosphomonoesterase
  • Uteroferrin

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF01569
Domain description: PAP2 superfamily
Occurring in:
  1. Acid phosphatase
The deposited structure of PDB entry 1eoi contains 3 copies of Pfam domain PF01569 (PAP2 superfamily) in Acid phosphatase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001011
Domain description: Acid phosphatase, class A, bacterial
Occurring in:
  1. Acid phosphatase
IPR000326
Domain description: Phosphatidic acid phosphatase type 2/haloperoxidase
Occurring in:
  1. Acid phosphatase
IPR018296
Domain description: Acid phosphatase, class A, bacterial, conserved site
Occurring in:
  1. Acid phosphatase
IPR036938
Domain description: Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Occurring in:
  1. Acid phosphatase

Structure domain

CATH CATH domain
1.20.144.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Vanadium-containing Chloroperoxidase; domain 1
Homology: Phosphatidic acid phosphatase type 2/haloperoxidase
Occurring in:
  1. Acid phosphatase
The deposited structure of PDB entry 1eoi contains 3 copies of CATH domain 1.20.144.10 (Vanadium-containing Chloroperoxidase; domain 1) in Acid phosphatase. Showing 1 copy in chain A.
SCOP SCOP annotation
48318
Class: All alpha proteins
Fold: Acid phosphatase/Vanadium-dependent haloperoxidase
Superfamily: Acid phosphatase/Vanadium-dependent haloperoxidase
Occurring in:
  1. Acid phosphatase
The deposited structure of PDB entry 1eoi contains 3 copies of SCOP domain 48318 (Type 2 phosphatidic acid phosphatase, PAP2) in Acid phosphatase. Showing 1 copy in chain A.