1eo8

X-ray diffraction
2.8Å resolution

INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dodecamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (6 distinct):
Hemagglutinin HA1 chain Chain: A
Molecule details ›
Chain: A
Length: 328 amino acids
Theoretical weight: 36.07 KDa
Source organism: Influenza A virus (A/X-31(H3N2))
UniProt:
  • Canonical: P03437 (Residues: 17-344; Coverage: 60%)
Gene name: HA
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin HA2 chain Chain: B
Molecule details ›
Chain: B
Length: 175 amino acids
Theoretical weight: 20.21 KDa
Source organism: Influenza A virus (A/X-31(H3N2))
UniProt:
  • Canonical: P03437 (Residues: 346-520; Coverage: 32%)
Gene name: HA
Structure domains: Hemagglutinin Ectodomain; Chain B
ANTIBODY (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 210 amino acids
Theoretical weight: 23.1 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
ANTIBODY (HEAVY CHAIN) Chain: H
Molecule details ›
Chain: H
Length: 217 amino acids
Theoretical weight: 23.41 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID2
Spacegroup: P321
Unit cell:
a: 138.15Å b: 138.15Å c: 129.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.196 0.298