1eh5

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1 COMPLEXED WITH PALMITATE

Released:

Function and Biology Details

Reaction catalysed:
Palmitoyl-[protein] + H(2)O = palmitate + [protein]
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Palmitoyl-protein thioesterase 1 Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 31.45 KDa
Source organism: Bos taurus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P45478 (Residues: 28-306; Coverage: 100%)
Gene names: CLN1, PPT, PPT1
Sequence domains: Palmitoyl protein thioesterase
Structure domains: alpha/beta hydrolase

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: P4122
Unit cell:
a: 67.52Å b: 67.52Å c: 128.92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.226 0.27
Expression system: Spodoptera frugiperda