X-ray diffraction
1.95Å resolution

ADRENODOXIN REDUCTASE in complex with NADP+ obtained by a soaking experiment


Function and Biology Details

Reaction catalysed:
2 reduced adrenodoxin + NADP(+) = 2 oxidized adrenodoxin + NADPH
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
NADPH:adrenodoxin oxidoreductase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 460 amino acids
Theoretical weight: 50.36 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P08165 (Residues: 33-492; Coverage: 94%)
Gene names: ADXR, FDXR
Sequence domains: Pyridine nucleotide-disulphide oxidoreductase
Structure domains:

Ligands and Environments

Cofactor: Ligand NAP 1 x NAP

Cofactor: Ligand FAD 1 x FAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P21
Unit cell:
a: 60.9Å b: 62.4Å c: 78.2Å
α: 90° β: 106.6° γ: 90°
R R work R free
0.184 0.184 0.227
Expression system: Escherichia coli BL21(DE3)