› 1dtz

X-ray diffraction
2.65Å resolution

STRUCTURE OF CAMEL APO-LACTOFERRIN DEMONSTRATES ITS DUAL ROLE IN SEQUESTERING AND TRANSPORTING FERRIC IONS SIMULTANEOUSLY:CRYSTAL STRUCTURE OF CAMEL APO-LACTOFERRIN AT 2.6A RESOLUTION.

Released:
DOI: 10.2210/pdb1dtz/pdb
PDB entry 1dtz coloured by chain, front view.
PDB entry 1dtz coloured by chain, side view.
PDB entry 1dtz coloured by chain, top view.
Source organism: Camelus dromedarius
Primary publication:
Camel lactoferrin, a transferrin-cum-lactoferrin: crystal structure of camel apolactoferrin at 2.6 A resolution and structural basis of its dual role.
Khan JA, Kumar P, Paramasivam M, Yadav RS, Sahani MS, Sharma S, Srinivasan A, Singh TP
J Mol Biol 309 751-61 (2001)
PMID: 11397094

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193582 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 689 amino acids
Theoretical weight: 75.45 KDa
Source organism: Camelus dromedarius
UniProt:
  • Canonical: Q9TUM0 (Residues: 20-708; Coverage: 100%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 175.84Å b: 80.92Å c: 56.35Å
α: 90° β: 92.35° γ: 90°
R-values:
R R work R free
0.216 0.198 0.266

Quick links

Citations

10 review citations

Lactoferrin a multiple bioactive protein: an overview.
García-Montoya et al. (2012)
9 more

3 mentions without citation

C-lobe of lactoferrin: the whole story of the half-molecule.
Sharma et al. (2013)
2 more