1dsf

X-ray diffraction
2Å resolution

THE CRYSTAL STRUCTURE OF THE DISULFIDE-STABILIZED FV FRAGMENT OF ANTICANCER ANTIBODY B1: CONFORMATIONAL INFLUENCE OF AN ENGINEERED DISULFIDE BOND

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-212992 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ANTICANCER ANTIBODY B1 Chain: L
Molecule details ›
Chain: L
Length: 112 amino acids
Theoretical weight: 12.22 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
Structure domains: Immunoglobulins
ANTICANCER ANTIBODY B1 Chain: H
Molecule details ›
Chain: H
Length: 119 amino acids
Theoretical weight: 13.25 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P6122
Unit cell:
a: 80.1Å b: 80.1Å c: 138.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.182 not available
Expression system: Escherichia coli BL21(DE3)