Assemblies
Assembly Name:
alpha-thrombin complex and Fibrinopeptide A
Multimeric state:
hetero trimer
Accessible surface area:
12244.03 Å2
Buried surface area:
4243.26 Å2
Dissociation area:
1,365.69
Å2
Dissociation energy (ΔGdiss):
16.69
kcal/mol
Dissociation entropy (TΔSdiss):
10.21
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-133067
Assembly Name:
Fibrinopeptide A and Thrombin light chain
Multimeric state:
hetero hexamer
Accessible surface area:
23472.2 Å2
Buried surface area:
9504.7 Å2
Dissociation area:
3,243.8
Å2
Dissociation energy (ΔGdiss):
23.94
kcal/mol
Dissociation entropy (TΔSdiss):
33.56
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-133149
Macromolecules
Chain: A
Length: 35 amino acids
Theoretical weight: 3.94 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Pfam: Thrombin light chain
InterPro:
SCOP: Eukaryotic proteases
Length: 35 amino acids
Theoretical weight: 3.94 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P00734 (Residues: 328-362; Coverage: 6%)
Pfam: Thrombin light chain
InterPro:
SCOP: Eukaryotic proteases
Chain: B
Length: 260 amino acids
Theoretical weight: 29.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Pfam: Trypsin
InterPro:
SCOP: Eukaryotic proteases
Length: 260 amino acids
Theoretical weight: 29.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P00734 (Residues: 363-622; Coverage: 44%)
Pfam: Trypsin
InterPro:
- Serine proteases, trypsin domain
- Peptidase S1, PA clan
- Peptidase S1, PA clan, chymotrypsin-like fold
- Peptidase S1A, chymotrypsin family
- Serine proteases, trypsin family, histidine active site
- Prothrombin/thrombin
SCOP: Eukaryotic proteases
Chain: C
Length: 11 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 11 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P02671 (Residues: 26-35; Coverage: 1%)