1dg6

X-ray diffraction
1.3Å resolution

CRYSTAL STRUCTURE OF APO2L/TRAIL

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor ligand superfamily member 10 Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 22.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P50591 (Residues: 91-281; Coverage: 68%)
Gene names: APO2L, TNFSF10, TRAIL
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R32
Unit cell:
a: 66.435Å b: 66.435Å c: 197.727Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.141 0.141 0.197
Expression system: Escherichia coli