Structure analysis

DNA (CYTOSINE-5) METHYLASE FROM HAEIII COVALENTLY BOUND TO DNA

X-ray diffraction
2.8Å resolution
Assembly composition:
hetero trimer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 18400 Å2
Buried surface area: 5700 Å2
Dissociation area: 1,500 Å2
Dissociation energy (ΔGdiss): 8 kcal/mol
Dissociation entropy (TΔSdiss): 12 kcal/mol
Interface energy (ΔGint): -16 kcal/mol
Symmetry number: 1
Assembly 2
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Multimeric state: hetero trimer
Accessible surface area: 17800 Å2
Buried surface area: 5500 Å2
Dissociation area: 1,500 Å2
Dissociation energy (ΔGdiss): 3 kcal/mol
Dissociation entropy (TΔSdiss): 12 kcal/mol
Interface energy (ΔGint): -14 kcal/mol
Symmetry number: 1

Macromolecules

Chains: A, B
Length: 324 amino acids
Theoretical weight: 37.09 KDa
Source organism: Haemophilus influenzae biotype aegyptius
UniProt:
  • Canonical: P20589 (Residues: 1-324; Coverage: 98%)
Gene name: haeIIIM
Pfam: C-5 cytosine-specific DNA methylase
InterPro:
CATH:
SCOP: C5 cytosine-specific DNA methylase, DCM

Search similar proteins

Name: DNA (5'-D(*AP*CP*CP*AP*GP*CP*AP*GP*GP*(C49)P*CP*AP*CP*CP*AP*GP*TP*G)-3')
Representative chains: F, G
Source organism: Haemophilus influenzae biotype aegyptius [725]
Expression system: Not provided
Length: 18 nucleotides
Theoretical weight: 5.56 KDa

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Name: DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*TP*GP*GP*(C5M)P*CP*TP*GP*CP*TP*GP*G)-3')
Representative chains: M, N
Source organism: Haemophilus influenzae biotype aegyptius [725]
Expression system: Not provided
Length: 18 nucleotides
Theoretical weight: 5.55 KDa

Search similar DNA