› 1db1

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D

Released:
DOI: 10.2210/pdb1db1/pdb
PDB 1db1 coloured by chain and viewed from the front.
PDB 1db1 coloured by chain and viewed from the side.
PDB 1db1 coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
Rochel N, Wurtz JM, Mitschler A, Klaholz B, Moras D
Mol. Cell 5 173-9 (2000)
PMID: 10678179

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vitamin D3 receptor Chain: A
Molecule details ›
Chain: A
Length: 259 amino acids
Theoretical weight: 29.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11473 (Residues: 118-427; Coverage: 61%)
Gene names: NR1I1, VDR
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:
Ligand VDX 1 x VDX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P212121
Unit cell:
a: 45.193Å b: 52.443Å c: 133.286Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.214
Expression system: Escherichia coli

Quick links

Citations

91 review citations

A Narrative Role of Vitamin D and Its Receptor: With Current Evidence on the Gastric Tissues.
Sirajudeen et al. (2019)
90 more

46 mentions without citation

Molecular Illustration in Research and Education: Past, Present, and Future.
Goodsell et al. (2018)
45 more