› 1d5v

Solution NMR

SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12)

Released:
DOI: 10.2210/pdb1d5v/pdb
PDB entry 1d5v coloured by chain, ensemble of 25 models, front view.
PDB entry 1d5v coloured by chain, ensemble of 25 models, side view.
PDB entry 1d5v coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11.
van Dongen MJ, Cederberg A, Carlsson P, Enerbäck S, Wikström M
J Mol Biol 296 351-9 (2000)
PMID: 10669593

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189289 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Forkhead box protein C2 Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 11.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99958 (Residues: 69-162; Coverage: 19%)
Gene names: FKHL14, FOXC2, MFH1
Sequence domains: Forkhead domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: COMBINED DISTANCE GEOMETRY/SIMULATING ANNEALING PROCEDURE
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Forkhead transcription factors: key players in development and metabolism.
Carlsson et al. (2002)
7 more

4 mentions without citation

Essential structural and functional determinants within the forkhead domain of FOXC1.
Saleem et al. (2004)
3 more