Function and Biology Details
Reactions catalysed:
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)
ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Bifunctional glutamate/proline--tRNA ligase (preferred)
PDBe Complex ID:
PDB-CPX-181933 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional glutamate/proline--tRNA ligase
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.72 KDa
Source organism: Cricetulus griseus
Expression system: Escherichia coli
UniProt:
Sequence domains: WHEP-TRS domain
Structure domains: S15/NS1, RNA-binding
Length: 59 amino acids
Theoretical weight: 6.72 KDa
Source organism: Cricetulus griseus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q7SIA2 (Residues: 825-874; Coverage: 3%)
Sequence domains: WHEP-TRS domain
Structure domains: S15/NS1, RNA-binding
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
DISTANCE GEOMETRY SIMULATED ANNEALING
Expression system: Escherichia coli
