Function and Biology

SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1

Source organism: Homo sapiens
Biochemical function: death domain binding
Biological process: regulation of apoptotic process
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00619
Domain description: Caspase recruitment domain
Occurring in:
  1. Apoptotic protease-activating factor 1
The deposited structure of PDB entry 1cww contains 1 copy of Pfam domain PF00619 (Caspase recruitment domain) in Apoptotic protease-activating factor 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR011029
Domain description: Death-like domain superfamily
Occurring in:
  1. Apoptotic protease-activating factor 1
IPR001315
Domain description: CARD domain
Occurring in:
  1. Apoptotic protease-activating factor 1
IPR037963
Domain description: Apoptotic Protease-Activating Factor 1, CARD domain
Occurring in:
  1. Apoptotic protease-activating factor 1
IPR037939
Domain description: Death domain-containing protein CRADD
Occurring in:
  1. Apoptotic protease-activating factor 1

Structure domain

CATH CATH domain
1.10.533.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Death Domain, Fas
Homology: Death Domain, Fas
Occurring in:
  1. Apoptotic protease-activating factor 1
The deposited structure of PDB entry 1cww contains 1 copy of CATH domain 1.10.533.10 (Death Domain, Fas) in Apoptotic protease-activating factor 1. Showing 1 copy in chain A.
SCOP SCOP annotation
81313
Class: All alpha proteins
Fold: DEATH domain
Superfamily: DEATH domain
Occurring in:
  1. Apoptotic protease-activating factor 1
The deposited structure of PDB entry 1cww contains 1 copy of SCOP domain 81313 (Caspase recruitment domain, CARD) in Apoptotic protease-activating factor 1. Showing 1 copy in chain A.