PDBe 1cwn

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF PORCINE ALDEHYDE REDUCTASE HOLOENZYME

Released:

Function and Biology Details

Reaction catalysed:
An alcohol + NADP(+) = an aldehyde + NADPH
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldo-keto reductase family 1 member A1 Chain: A
Molecule details ›
Chain: A
Length: 324 amino acids
Theoretical weight: 36.45 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: NEW P50578 (Residues: 2-325; Coverage: 100%)
Gene names: AKR1A1, ALR, ALR1
Sequence domains: Aldo/keto reductase family

Ligands and Environments


Cofactor: Ligand NAP 1 x NAP
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P6522
Unit cell:
a: 67.2Å b: 67.2Å c: 243.7Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.2 not available