1cnt

X-ray diffraction
2.4Å resolution

CILIARY NEUROTROPHIC FACTOR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ciliary neurotrophic factor Chains: 1, 2, 3, 4
Molecule details ›
Chains: 1, 2, 3, 4
Length: 187 amino acids
Theoretical weight: 21.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P26441 (Residues: 1-187; Coverage: 94%)
Gene name: CNTF
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 52.95Å b: 62.09Å c: 208.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.247
Expression system: Escherichia coli