1ck7

X-ray diffraction
2.8Å resolution

GELATINASE A (FULL-LENGTH)

Released:

Function and Biology Details

Reaction catalysed:
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
72 kDa type IV collagenase Chain: A
Molecule details ›
Chain: A
Length: 631 amino acids
Theoretical weight: 71 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P08253 (Residues: 30-660; Coverage: 100%)
Gene names: CLG4A, MMP2
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM02
Spacegroup: I4122
Unit cell:
a: 121.32Å b: 121.32Å c: 345.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.286 0.286 0.327
Expression system: Trichoplusia ni