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HUMAN CYTOSOLIC PHOSPHOLIPASE A2

X-ray diffraction
2.5Å resolution
PDB entry 1cjy coloured by chain, front view.
PDB entry 1cjy coloured by chain, side view.
PDB entry 1cjy coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Cytosolic phospholipase A2
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Multimeric state: monomeric
Accessible surface area: 25934.59 Å2
Buried surface area: 631.41 Å2
Dissociation area: 243.8 Å2
Dissociation energy (ΔGdiss): -2.66 kcal/mol
Dissociation entropy (TΔSdiss): 2.81 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-155641
Assembly 2
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Assembly Name: Cytosolic phospholipase A2
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Multimeric state: monomeric
Accessible surface area: 24750.4 Å2
Buried surface area: 623.03 Å2
Dissociation area: 239.59 Å2
Dissociation energy (ΔGdiss): -2.04 kcal/mol
Dissociation entropy (TΔSdiss): 2.84 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-155641

Macromolecules

Cytosolic phospholipase A2
Chains: A, B
Length: 749 amino acids
Theoretical weight: 85.31 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P47712 (Residues: 1-749; Coverage: 100%)
Gene names: CPLA2, PLA2G4, PLA2G4A
Pfam:
InterPro:
CATH:
SCOP:
Cytosolic phospholipase A2 in PDB entry 1cjy, assembly 1, front view.
Cytosolic phospholipase A2 in PDB entry 1cjy, assembly 1, side view.
Cytosolic phospholipase A2 in PDB entry 1cjy, assembly 1, top view.
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