› 1chl

Solution NMR

NMR SEQUENTIAL ASSIGNMENTS AND SOLUTION STRUCTURE OF CHLOROTOXIN, A SMALL SCORPION TOXIN THAT BLOCKS CHLORIDE CHANNELS

Released:
DOI: 10.2210/pdb1chl/pdb
PDB entry 1chl coloured by chain, ensemble of 7 models, front view.
PDB entry 1chl coloured by chain, ensemble of 7 models, side view.
PDB entry 1chl coloured by chain, ensemble of 7 models, top view.
Source organism: Leiurus quinquestriatus
Primary publication:
NMR sequential assignments and solution structure of chlorotoxin, a small scorpion toxin that blocks chloride channels.
Lippens G, Najib J, Wodak SJ, Tartar A
Biochemistry 34 13-21 (1995)
PMID: 7819188

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155324 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chlorotoxin Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 4.01 KDa
Source organism: Leiurus quinquestriatus
Expression system: Not provided
UniProt:
  • Canonical: P45639 (Residues: 1-36; Coverage: 100%)
Sequence domains: Scorpion short toxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

24 review citations

Scorpion toxins specific for Na+-channels.
Possani et al. (1999)
23 more

19 mentions without citation

Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion.
Dardevet et al. (2015)
18 more