Structure analysis

MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI

X-ray diffraction
2.1Å resolution
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 10500 Å2
Buried surface area: 2900 Å2
Dissociation area: 1,200 Å2
Dissociation energy (ΔGdiss): 4 kcal/mol
Dissociation entropy (TΔSdiss): 11 kcal/mol
Interface energy (ΔGint): -102 kcal/mol
Symmetry number: 1

Macromolecules

Chain: L
Length: 113 amino acids
Theoretical weight: 12.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01631 (Residues: 1-113; Coverage: 100%)
Pfam: Immunoglobulin V-set domain
InterPro:
CATH: Immunoglobulins
SCOP: V set domains (antibody variable domain-like)

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Chain: H
Length: 119 amino acids
Theoretical weight: 13.19 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P18524 (Residues: 20-117; Coverage: 100%)
Pfam: Immunoglobulin V-set domain
InterPro:
CATH: Immunoglobulins
SCOP: V set domains (antibody variable domain-like)

Search similar proteins