1c72

X-ray diffraction
2.8Å resolution

TYR115, GLN165 AND TRP209 CONTRIBUTE TO THE 1,2-EPOXY-3-(P-NITROPHENOXY)PROPANE CONJUGATING ACTIVITIES OF GLUTATHIONE S-TRANSFERASE CGSTM1-1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 219 amino acids
Theoretical weight: 25.78 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P20136 (Residues: 2-220; Coverage: 100%)
Gene name: GSTM2
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand EPY 4 x EPY
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: C2221
Unit cell:
a: 125.6Å b: 136.65Å c: 125.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 0.28
Expression system: Escherichia coli