1c2o

X-ray diffraction
4.2Å resolution

ELECTROPHORUS ELECTRICUS ACETYLCHOLINESTERASE

Released:

Function and Biology Details

Reaction catalysed:
Acetylcholine + H(2)O = choline + acetate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholinesterase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 539 amino acids
Theoretical weight: 59.29 KDa
Source organism: Electrophorus electricus
UniProt:
  • Canonical: P21836 (Residues: 36-574; Coverage: 93%)
Gene name: Ache
Sequence domains: Carboxylesterase family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 211.16Å b: 129.75Å c: 195.42Å
α: 90° β: 103.2° γ: 90°
R-values:
R R work R free
0.375 0.375 0.385