1bx4

X-ray diffraction
1.5Å resolution

STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.50 ANGSTROMS

Released:
Source organism: Homo sapiens
Entry authors: Mathews II, Erion MD, Ealick SE

Function and Biology Details

Reaction catalysed:
ATP + adenosine = ADP + AMP
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine kinase Chain: A
Molecule details ›
Chain: A
Length: 345 amino acids
Theoretical weight: 38.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55263 (Residues: 20-362; Coverage: 95%)
  • Best match: P55263-2 (Residues: 1-345)
Gene name: ADK
Sequence domains: pfkB family carbohydrate kinase
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21212
Unit cell:
a: 65.3Å b: 111.08Å c: 49.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.192 0.226
Expression system: Escherichia coli