1bun

X-ray diffraction
2.45Å resolution

STRUCTURE OF BETA2-BUNGAROTOXIN: POTASSIUM CHANNEL BINDING BY KUNITZ MODULES AND TARGETED PHOSPHOLIPASE ACTION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Basic phospholipase A2 beta-bungarotoxin A1 chain Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 13.52 KDa
Source organism: Bungarus multicinctus
UniProt:
  • Canonical: P00617 (Residues: 28-147; Coverage: 94%)
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain
Kunitz-type serine protease inhibitor homolog beta-bungarotoxin B2 chain Chain: B
Molecule details ›
Chain: B
Length: 61 amino acids
Theoretical weight: 7.21 KDa
Source organism: Bungarus multicinctus
UniProt:
  • Canonical: P00989 (Residues: 25-85; Coverage: 100%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P4322
Unit cell:
a: 52.6Å b: 52.6Å c: 177.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.281