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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE TYPE II ACTIVIN RECEPTOR

Source organism: Mus musculus
Biochemical function: ATP binding
Biological process: cell surface receptor protein serine/threonine kinase signaling pathway
Cellular component: membrane

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EC 2.7.11.30: Receptor protein serine/threonine kinase

Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Systematic name:
ATP:[receptor-protein] phosphotransferase
Alternative Name(s):
  • Activin receptor kinase
  • Receptor serine/threonine protein kinase
  • Receptor type I serine/threonine protein kinase
  • Receptor type II serine/threonine protein kinase
  • STK13
  • TGF-beta kinase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01064
Domain description: Activin types I and II receptor domain
Occurring in:
  1. Activin receptor type-2A
The deposited structure of PDB entry 1bte contains 2 copies of Pfam domain PF01064 (Activin types I and II receptor domain) in Activin receptor type-2A. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000333
Domain description: Ser/Thr protein kinase, TGFB receptor
Occurring in:
  1. Activin receptor type-2A
IPR045860
Domain description: Snake toxin-like superfamily
Occurring in:
  1. Activin receptor type-2A
IPR000472
Domain description: Activin types I and II receptor domain
Occurring in:
  1. Activin receptor type-2A

Structure domain

CATH CATH domain
2.10.60.10
Class: Mainly Beta
Architecture: Ribbon
Topology: CD59
Homology: CD59
Occurring in:
  1. Activin receptor type-2A
The deposited structure of PDB entry 1bte contains 2 copies of CATH domain 2.10.60.10 (CD59) in Activin receptor type-2A. Showing 1 copy in chain B.
SCOP SCOP annotation
57354
Class: Small proteins
Fold: Snake toxin-like
Superfamily: Snake toxin-like
Occurring in:
  1. Activin receptor type-2A
The deposited structure of PDB entry 1bte contains 2 copies of SCOP domain 57354 (Extracellular domain of cell surface receptors) in Activin receptor type-2A. Showing 1 copy in chain B.

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