PDBe 1br9

X-ray diffraction
2.1Å resolution

HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metalloproteinase inhibitor 2 Chain: A
Molecule details ›
Chain: A
Length: 194 amino acids
Theoretical weight: 21.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P16035 (Residues: 27-220; Coverage: 100%)
Gene name: TIMP2
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P21212
Unit cell:
a: 72.05Å b: 52.7Å c: 46.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.238 0.271
Expression system: Trichoplusia ni