1boa

X-ray diffraction
1.8Å resolution

HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH ANGIOGENESIS INHIBITOR FUMAGILLIN

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methionine aminopeptidase 2 Chain: A
Molecule details ›
Chain: A
Length: 478 amino acids
Theoretical weight: 52.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P50579 (Residues: 1-478; Coverage: 100%)
Gene names: METAP2, MNPEP, P67EIF2
Sequence domains: Metallopeptidase family M24
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: C2221
Unit cell:
a: 90.7Å b: 99.58Å c: 101.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.232
Expression system: Spodoptera frugiperda