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RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE

X-ray diffraction
2.8Å resolution
PDB entry 1bg3 coloured by chain, front view.
PDB entry 1bg3 coloured by chain, side view.
PDB entry 1bg3 coloured by chain, top view.
Source organism: Rattus norvegicus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hexokinase-1
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Multimeric state: monomeric
Accessible surface area: 33950.45 Å2
Buried surface area: 1810.83 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138747
Assembly 2
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Assembly Name: Hexokinase-1
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Multimeric state: monomeric
Accessible surface area: 34657.11 Å2
Buried surface area: 1813.9 Å2
Dissociation area: 206.77 Å2
Dissociation energy (ΔGdiss): -3.17 kcal/mol
Dissociation entropy (TΔSdiss): 2.58 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138747

Macromolecules

Hexokinase-1
Chains: A, B
Length: 918 amino acids
Theoretical weight: 102.55 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P05708 (Residues: 1-918; Coverage: 100%)
Gene name: Hk1
Pfam:
InterPro:
CATH:
SCOP: Hexokinase
Hexokinase-1 in PDB entry 1bg3, assembly 1, front view.
Hexokinase-1 in PDB entry 1bg3, assembly 1, side view.
Hexokinase-1 in PDB entry 1bg3, assembly 1, top view.
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