1bg3

X-ray diffraction
2.8Å resolution

RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE

Released:
Source organism: Rattus norvegicus
Primary publication:
The structure of mammalian hexokinase-1.
Nat. Struct. Biol. 5 555-60 (1998)
PMID: 9665168

Function and Biology Details

Reaction catalysed:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hexokinase-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 918 amino acids
Theoretical weight: 102.55 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P05708 (Residues: 1-918; Coverage: 100%)
Gene name: Hk1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P21
Unit cell:
a: 132.1Å b: 77.1Å c: 137.1Å
α: 90° β: 96° γ: 90°
R-values:
R R work R free
0.196 0.196 0.251