Assemblies
Assembly Name:
Signal transducer and activator of transcription 3 and DNA
Multimeric state:
hetero tetramer
Accessible surface area:
57878.23 Å2
Buried surface area:
7022.82 Å2
Dissociation area:
1,462.01
Å2
Dissociation energy (ΔGdiss):
30.69
kcal/mol
Dissociation entropy (TΔSdiss):
12.27
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-113487
Macromolecules
Chain: A
Length: 596 amino acids
Theoretical weight: 68.22 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
Pfam:
Length: 596 amino acids
Theoretical weight: 68.22 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P42227 (Residues: 127-715; Coverage: 77%)
Pfam:
- STAT protein, all-alpha domain
- STAT protein, DNA binding domain
- Signal transducer and activator of transcription, linker domain
- SH2 domain
- Transcription factor STAT
- STAT transcription factor, coiled coil
- STAT transcription factor, all-alpha domain
- p53-like transcription factor, DNA-binding domain superfamily
- STAT transcription factor, DNA-binding, N-terminal
- STAT transcription factor, DNA-binding
- STAT3, SH2 domain
- SH2 domain superfamily
- SH2 domain
- STAT transcription factor, all-alpha domain
- STAT transcription factor, DNA-binding domain
- EF-hand
- SH2 domain
Name:
DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*CP*T)-3')
Representative chains: B
Source organism: Mus musculus [10090]
Expression system: Not provided
Length: 18 nucleotides
Theoretical weight: 5.44 KDa
Representative chains: B
Source organism: Mus musculus [10090]
Expression system: Not provided
Length: 18 nucleotides
Theoretical weight: 5.44 KDa
