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THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS

X-ray diffraction
1.9Å resolution
PDB entry 1bas coloured by chain, front view.
PDB entry 1bas coloured by chain, side view.
PDB entry 1bas coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fibroblast growth factor 2
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Multimeric state: monomeric
Accessible surface area: 6028.79 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-140533

Macromolecules

Fibroblast growth factor 2
Chain: A
Length: 154 amino acids
Theoretical weight: 17.12 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09038 (Residues: 135-288; Coverage: 54%)
Gene names: FGF2, FGFB
Pfam: Fibroblast growth factor
InterPro:
CATH: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
SCOP: Fibroblast growth factors (FGF)
Fibroblast growth factor 2 in PDB entry 1bas, assembly 1, front view.
Fibroblast growth factor 2 in PDB entry 1bas, assembly 1, side view.
Fibroblast growth factor 2 in PDB entry 1bas, assembly 1, top view.
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