› 1ba9

Solution NMR

THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES

Released:
DOI: 10.2210/pdb1ba9/pdb
PDB entry 1ba9 coloured by chain, ensemble of 36 models, front view.
PDB entry 1ba9 coloured by chain, ensemble of 36 models, side view.
PDB entry 1ba9 coloured by chain, ensemble of 36 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?.
Banci L, Benedetto M, Bertini I, Del Conte R, Piccioli M, Viezzoli MS
Biochemistry 37 11780-91 (1998)
PMID: 9718300

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 15.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand CU1 1 x CU1
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORTION ANGLES DYNAMIC (DYANA)
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology.
Matés JM. (2000)
7 more

9 mentions without citation

Posttranslational modifications in Cu,Zn-superoxide dismutase and mutations associated with amyotrophic lateral sclerosis.
Furukawa et al. (2006)
8 more