› 1b9w

X-ray diffraction
1.8Å resolution

C-TERMINAL MEROZOITE SURFACE PROTEIN 1 FROM PLASMODIUM CYNOMOLGI

Released:
DOI: 10.2210/pdb1b9w/pdb
PDB entry 1b9w coloured by chain, front view.
PDB entry 1b9w coloured by chain, side view.
PDB entry 1b9w coloured by chain, top view.
Source organism: Plasmodium cynomolgi
Primary publication:
The crystal structure of C-terminal merozoite surface protein 1 at 1.8 A resolution, a highly protective malaria vaccine candidate.
Chitarra V, Holm I, Bentley GA, Pêtres S, Longacre S
Mol Cell 3 457-64 (1999)
PMID: 10230398

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173223 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Merozoite surface protein 1 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.8 KDa
Source organism: Plasmodium cynomolgi
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q25659 (Residues: 291-379; Coverage: 24%)
Gene name: MSP1
Sequence domains: MSP1 EGF domain 1
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P3221
Unit cell:
a: 43.77Å b: 43.77Å c: 92.04Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.212 0.279
Expression system: Trichoplusia ni

Quick links

Citations

18 review citations

Invasion of red blood cells by malaria parasites.
Cowman et al. (2006)
17 more

4 mentions without citation

Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Parker et al. (2016)
3 more