Function and Biology

STRUCTURE OF THE HOMEOTIC UBX/EXD/DNA TERNARY COMPLEX

Source organism: Drosophila melanogaster
Biochemical function: DNA binding
Biological process: regulation of DNA-templated transcription
Cellular component: nucleus

Sequence families

Pfam Protein families (Pfam)
PF05920
Domain description: Homeobox KN domain
Occurring in:
  1. Homeobox protein extradenticle
The deposited structure of PDB entry 1b8i contains 1 copy of Pfam domain PF05920 (Homeobox KN domain) in Homeobox protein extradenticle. Showing 1 copy in chain D [auth B].

PF00046
Domain description: Homeodomain
Occurring in:
  1. Homeotic protein ultrabithorax
The deposited structure of PDB entry 1b8i contains 1 copy of Pfam domain PF00046 (Homeodomain) in Homeotic protein ultrabithorax. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR001356
Domain description: Homeobox domain
Occurring in:
  1. Homeotic protein ultrabithorax
  2. Homeobox protein extradenticle
IPR020479
Domain description: Homeobox domain, metazoa
Occurring in:
  1. Homeotic protein ultrabithorax
IPR017970
Domain description: Homeobox, conserved site
Occurring in:
  1. Homeotic protein ultrabithorax
  2. Homeobox protein extradenticle
IPR000047
Domain description: Helix-turn-helix motif
Occurring in:
  1. Homeotic protein ultrabithorax
IPR009057
Domain description: Homeobox-like domain superfamily
Occurring in:
  1. Homeotic protein ultrabithorax
  2. Homeobox protein extradenticle
IPR017995
Domain description: Homeobox protein, antennapedia type
Occurring in:
  1. Homeotic protein ultrabithorax
IPR001827
Domain description: Homeobox protein, antennapedia type, conserved site
Occurring in:
  1. Homeotic protein ultrabithorax

Structure domain

CATH CATH domain
1.10.10.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeodomain-like
Occurring in:
  1. Homeotic protein ultrabithorax
  2. Homeobox protein extradenticle
The deposited structure of PDB entry 1b8i contains 1 copy of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in Homeotic protein ultrabithorax. Showing 1 copy in chain C [auth A].
The deposited structure of PDB entry 1b8i contains 1 copy of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in Homeobox protein extradenticle. Showing 1 copy in chain D [auth B].
SCOP SCOP annotation
46690
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Occurring in:
  1. Homeotic protein ultrabithorax
  2. Homeobox protein extradenticle
The deposited structure of PDB entry 1b8i contains 1 copy of SCOP domain 46690 (Homeodomain) in Homeotic protein ultrabithorax. Showing 1 copy in chain C [auth A].
The deposited structure of PDB entry 1b8i contains 1 copy of SCOP domain 46690 (Homeodomain) in Homeobox protein extradenticle. Showing 1 copy in chain D [auth B].