1b37

X-ray diffraction
1.9Å resolution

A 30 ANGSTROM U-SHAPED CATALYTIC TUNNEL IN THE CRYSTAL STRUCTURE OF POLYAMINE OXIDASE

Released:

Function and Biology Details

Reactions catalysed:
Spermidine + O(2) + H(2)O = propane-1,3-diamine + 4-aminobutanal + H(2)O(2)
N(8)-acetylspermidine + O(2) + H(2)O = propane-1,3-diamine + 4-acetamidobutanal + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric
homo hexamer (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Polyamine oxidase 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 472 amino acids
Theoretical weight: 53.7 KDa
Source organism: Zea mays
UniProt:
  • Canonical: O64411 (Residues: 29-500; Coverage: 100%)
Gene names: MPAO, MPAO1, PAO
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 3 x FAD
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, MAN, FCA
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P6522
Unit cell:
a: 184.8Å b: 184.8Å c: 282.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 not available not available