› › Function and Biology

CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION

Source organism: Bos taurus
Biochemical function: heparin binding
Biological process: regulation of blood coagulation
Cellular component: extracellular space

Quick links

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00079
Domain description: Serpin (serine protease inhibitor)
Occurring in:
  1. Antithrombin-III
The deposited structure of PDB entry 1att contains 2 copies of Pfam domain PF00079 (Serpin (serine protease inhibitor)) in Antithrombin-III. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR023796
Domain description: Serpin domain
Occurring in:
  1. Antithrombin-III
IPR033829
Domain description: Antithrombin-III, serpin domain
Occurring in:
  1. Antithrombin-III
IPR023795
Domain description: Serpin, conserved site
Occurring in:
  1. Antithrombin-III
IPR042185
Domain description: Serpin superfamily, domain 2
Occurring in:
  1. Antithrombin-III
IPR042178
Domain description: Serpin superfamily, domain 1
Occurring in:
  1. Antithrombin-III
IPR000215
Domain description: Serpin family
Occurring in:
  1. Antithrombin-III
IPR036186
Domain description: Serpin superfamily
Occurring in:
  1. Antithrombin-III

Structure domains

CATH CATH domains
2.30.39.10
Class: Mainly Beta
Architecture: Roll
Topology: Alpha-1-antitrypsin; domain 1
Homology: Alpha-1-antitrypsin, domain 1
Occurring in:
  1. Antithrombin-III
The deposited structure of PDB entry 1att contains 2 copies of CATH domain 2.30.39.10 (Alpha-1-antitrypsin; domain 1) in Antithrombin-III. Showing 1 copy in chain A.
3.30.497.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Antithrombin; Chain I, domain 2
Homology: Antithrombin, subunit I, domain 2
Occurring in:
  1. Antithrombin-III
The deposited structure of PDB entry 1att contains 2 copies of CATH domain 3.30.497.10 (Antithrombin; Chain I, domain 2) in Antithrombin-III. Showing 1 copy in chain A.
SCOP SCOP annotation
56575
Class: Multi-domain proteins (alpha and beta)
Fold: Serpins
Superfamily: Serpins
Occurring in:
  1. Antithrombin-III
The deposited structure of PDB entry 1att contains 2 copies of SCOP domain 56575 (Serpins) in Antithrombin-III. Showing 1 copy in chain A.

Quick links