Function and Biology

COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT

Source organism: Xenopus laevis
Biochemical function: DNA binding
Biological process: DNA-templated transcription, initiation
Cellular component: nucleosome

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF15511
Domain description: Centromere kinetochore component CENP-T histone fold
Occurring in:
  1. Histone H4
1 copy of Pfam domain PF15511 (Centromere kinetochore component CENP-T histone fold) in Histone H4 in PDB 1aoi.

InterPro InterPro annotations
IPR001951
Domain description: Histone H4
Occurring in:
  1. Histone H4
IPR002119
Domain description: Histone H2A
Occurring in:
  1. Histone H2A type 1
IPR009072
Domain description: Histone-fold
Occurring in:
  1. Histone H3.3C
  2. Histone H4
  3. Histone H2A type 1
  4. Histone H2B 1.1
IPR000558
Domain description: Histone H2B
Occurring in:
  1. Histone H2B 1.1
IPR007125
Domain description: Histone H2A/H2B/H3
Occurring in:
  1. Histone H3.3C
  2. Histone H2A type 1
  3. Histone H2B 1.1
IPR000164
Domain description: Histone H3/CENP-A
Occurring in:
  1. Histone H3.3C
IPR032454
Domain description: Histone H2A, C-terminal domain
Occurring in:
  1. Histone H2A type 1
IPR004823
Domain description: TATA box binding protein associated factor (TAF)
Occurring in:
  1. Histone H4
IPR035425
Domain description: CENP-T/Histone H4, histone fold
Occurring in:
  1. Histone H4

Structure domain

CATH CATH domain
1.10.20.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Histone, subunit A
Homology: Histone, subunit A
Occurring in:
  1. Histone H3.3C
  2. Histone H4
  3. Histone H2A type 1
  4. Histone H2B 1.1
3 copies of CATH domain 1.10.20.10 (Histone, subunit A) in Histone H3.3C in PDB 1aoi.
4 copies of CATH domain 1.10.20.10 (Histone, subunit A) in Histone H4 in PDB 1aoi.
1 copy of CATH domain 1.10.20.10 (Histone, subunit A) in Histone H2A type 1 in PDB 1aoi.
2 copies of CATH domain 1.10.20.10 (Histone, subunit A) in Histone H2B 1.1 in PDB 1aoi.
SCOP SCOP annotation
47114
Class: All alpha proteins
Fold: Histone-fold
Superfamily: Histone-fold
Occurring in:
  1. Histone H3.3C
  2. Histone H4
  3. Histone H2A type 1
  4. Histone H2B 1.1
3 copies of SCOP domain 47114 (Nucleosome core histones) in Histone H3.3C in PDB 1aoi.
4 copies of SCOP domain 47114 (Nucleosome core histones) in Histone H4 in PDB 1aoi.
1 copy of SCOP domain 47114 (Nucleosome core histones) in Histone H2A type 1 in PDB 1aoi.
2 copies of SCOP domain 47114 (Nucleosome core histones) in Histone H2B 1.1 in PDB 1aoi.