1acl

X-ray diffraction
2.8Å resolution

QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 537 amino acids
Theoretical weight: 60.79 KDa
Source organism: Tetronarce californica
Expression system: Not provided
UniProt:
  • Canonical: P04058 (Residues: 22-556; Coverage: 95%)
  • Best match: P04058-2 (Residues: 22-558)
Gene name: ache
Sequence domains: Carboxylesterase family
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 113.05Å b: 113.05Å c: 137.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.199 not available
Expression system: Not provided