› 1a2v

X-ray diffraction
2.4Å resolution

COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA

Released:
DOI: 10.2210/pdb1a2v/pdb
PDB entry 1a2v coloured by chain, front view.
PDB entry 1a2v coloured by chain, side view.
PDB entry 1a2v coloured by chain, top view.
Source organism: Ogataea angusta
Primary publication:
Crystallographic study of yeast copper amine oxidase.
Li R, Chen L, Cai D, Klinman JP, Mathews FS
Acta Crystallogr D Biol Crystallogr 53 364-70 (1997)
PMID: 15299901

Function and Biology Details

Reaction catalysed: 
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146322 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal primary amine oxidase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 655 amino acids
Theoretical weight: 73.69 KDa
Source organism: Ogataea angusta
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P12807 (Residues: 18-672; Coverage: 95%)
Gene name: AMO
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CU 6 x CU
1 modified residue:
Ligand TPQ 6 x TPQ

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 138.77Å b: 148.22Å c: 234.01Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 0.224
Expression system: Saccharomyces cerevisiae

Quick links

Citations

3 citation in other articles

Copper amine oxidase from Hansenula polymorpha: the crystal structure determined at 2.4 A resolution reveals the active conformation.
Li et al. (1998)
2 more

5 mentions without citation

Copper active sites in biology.
Solomon et al. (2014)
4 more