PDBe 1a15

X-ray diffraction
2.2Å resolution

SDF-1ALPHA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Stromal cell-derived factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 67 amino acids
Theoretical weight: 7.81 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P48061 (Residues: 22-88; Coverage: 93%)
  • Best match: P48061-7 (Residues: 22-38)
Gene names: CXCL12, SDF1, SDF1A, SDF1B
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P212121
Unit cell:
a: 38.84Å b: 50.47Å c: 64.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.298
Expression system: Not provided