1zl8

Solution NMR

NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
LIN-7 Chain: A
Molecule details ›
Chain: A
Length: 53 amino acids
Theoretical weight: 6.09 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P90976 (Residues: 116-165; Coverage: 17%)
Structure domains: L27 domain
Peripheral plasma membrane protein CASK Chain: B
Molecule details ›
Chain: B
Length: 54 amino acids
Theoretical weight: 6.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O14936 (Residues: 403-456; Coverage: 6%)
Gene names: CASK, LIN2
Structure domains: L27 domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Escherichia coli BL21