PDBe 1yyh

X-ray diffraction
1.9Å resolution

Crystal structure of the human Notch 1 ankyrin domain


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Notch 1 intracellular domain Chains: A, B
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 27.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P46531 (Residues: 1872-2114; Coverage: 10%)
Gene names: NOTCH1, TAN1
Sequence domains:
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P65
Unit cell:
a: 96.84Å b: 96.84Å c: 108.996Å
α: 90° β: 90° γ: 120°
R R work R free
0.163 0.161 0.193
Expression system: Escherichia coli