PDBe 1yxq

X-ray diffraction
2.01Å resolution

Crystal structure of actin in complex with swinholide A

Released:
Source organism: Oryctolagus cuniculus
Primary publication:
Structural basis of swinholide A binding to actin.
Chem. Biol. 12 287-91 (2005)
PMID: 15797212

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 68Å b: 76.8Å c: 98.4Å
α: 90° β: 101.2° γ: 90°
R-values:
R R work R free
0.186 0.184 0.219