X-ray diffraction
1.9Å resolution

Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae

Source organism: Vibrio cholerae
Entry authors: Kumaran D, Swaminathan S, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
HTH cro/C1-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.96 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
  • Canonical: Q9KQN0 (Residues: 2-180; Coverage: 99%)
Gene name: VC_1968
Sequence domains: Helix-turn-helix
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P3121
Unit cell:
a: 79.226Å b: 79.226Å c: 49.849Å
α: 90° β: 90° γ: 120°
R R work R free
0.228 0.199 0.224
Expression system: Escherichia coli