1y63

X-ray diffraction
1.7Å resolution

Initial crystal structural analysis of a probable kinase from Leishmania major Friedlin

Released:
Entry authors: Robien MA, Hol WGJ, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Reaction catalysed:
ATP + AMP = 2 ADP
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate kinase isoenzyme 6 homolog Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 21.26 KDa
Source organism: Leishmania major strain Friedlin
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4Q7A6 (Residues: 1-180; Coverage: 100%)
Gene name: LMJF_30_1890
Sequence domains: AAA domain
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P4212
Unit cell:
a: 107.116Å b: 107.116Å c: 35.216Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.196
Expression system: Escherichia coli