› 1y2p

Solution NMR

Solution structure of Hstx3P

Released:
DOI: 10.2210/pdb1y2p/pdb
PDB entry 1y2p coloured by chain, ensemble of 20 models, front view.
PDB entry 1y2p coloured by chain, ensemble of 20 models, side view.
PDB entry 1y2p coloured by chain, ensemble of 20 models, top view.
Source organism: Heterometrus spinifer
Primary publication:
The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily.
Carrega L, Mosbah A, Ferrat G, Beeton C, Andreotti N, Mansuelle P, Darbon H, De Waard M, Sabatier JM
Proteins 61 1010-23 (2005)
PMID: 16247791

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157931 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 6.3 Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 3.84 KDa
Source organism: Heterometrus spinifer
Expression system: Not provided
UniProt:
  • Canonical: P59867 (Residues: 1-34; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Not provided

Quick links

Citations

2 review citations

Early engineering approaches to improve peptide developability and manufacturability.
Furman et al. (2015)
1 more